Tech Transfer eNews Blog

Medical College of Wisconsin start-up develops method to deliver cancer drugs without harming healthy cells


By Jesse Schwartz
Published: November 15th, 2017

A start-up from the Medical College of Wisconsin (MCW) is developing a technology that could allow doctors to deliver drugs directly to cancer cells while leaving healthy ones unharmed.

NanoRED was formed when a group of students and post-docs worked together at the Nanotechnology Startup Challenge in Cancer, a program launched by the National Cancer Institute and the Center for Advancing Innovation. The team, led by MCW student Johnathan Ebben and Blood Center of Wisconsin post-doc Gang Xin, created a way to use IR-triggered liposomes to deliver cancer treatments directly to tumors.

“All of the targeted molecular therapies that exist right now aren’t effective,” says Ebben. “This technology leapfrogs all of that because we can directly release many different drugs right where we want it in the tumor microenvironment.”

NanoRED has participated in the I-Corps program at the University of Wisconsin-Milwaukee and is the winner of the life sciences category in the 2017 Governor’s Business Plan Contest. Both of these entrepreneurship programs have provided the start-up with grant funding, business resources and mentorship.

NanoRED is putting its technology through pre-clinical experiments at MCW, with the goal of reaching clinical trials in about three years. To accomplish that, says Ebben, NanoRED needs to license each molecular therapy to a few different pharmaceutical groups.

“Once we can show that we can deliver a molecule to a tumor without affecting the rest of the body, it’s a way for us to potentially collaborate with a lot of different people to advance many different therapies,” Ebben says.

Source: BizTimes

Posted under: Tech Transfer e-News

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