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UC Irvine licenses out stem cell technology to enable the study of Alzheimer’s and other diseases


By Jesse Schwartz
Published: June 13th, 2018

FUJIFILM Cellular Dynamics (FCDI) and the University of California-Irvine (UCI) have entered into a licensing agreement to commercialize a technology that could help researchers develop new treatments for degenerative neurological diseases.

The technology is a technique to formulate microglia cells, which play a critical role in preserving brain function. FCDI specializes in human induced pluripotent stem cells (iPSCs) and differentiated tissue-specific iPSCs. The license from UCI Applied Innovation, the university’s commercialization arm, would enable FCDI to differentiate iPSCs into microglia cells, which would help researchers study degenerative neurological diseases such as Alzheimer’s.

“Until now, researchers have relied predominantly on animal models, which do not sufficiently mimic the human disease, to study the role microglia play in neurodegeneration,” says Seimi Satake, chairman and CEO of FCDI.

“With UCI’s technology, FCDI will bring to market iPSC-derived microglia that will provide researchers with better tools to characterize microglia from donors with neurological diseases, to develop assays that distinguish between normal and diseased behaviors, and to advance efforts in discovering new therapies,” Satake says.

“We are pleased that FCDI has licensed our protocol to make and distribute microglia to the scientific community,” comment professors Wayne Poon and Edsel Abud, co-inventors of the technology along with professor Matt Blurton-Jones. “As leaders in the field of providing iPSC-derived products, we are confident that FCDI will provide researchers and scientists with a reliable product in large scale to carry out quality studies.”

Source: PR Newswire

Posted under: Tech Transfer e-News

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