Industry-Sponsored Research Week

Monash U and Janssen collaboration aims to improve diagnosis and treatment of celiac disease


By David Schwartz
Published: June 23rd, 2020

A multiyear research collaboration between Monash University and Janssen Biotech seeks to better understand the immune mechanisms behind celiac disease, which they hope will pave the way for new ways to diagnose and treat the condition.

The collaboration, facilitated by Monash Innovation and Johnson & Johnson Innovation LLC, will be headed up by Professor Jamie Rossjohn from the Monash Biomedicine Discovery Institute.

Celiac disease, which affects approximately 1% of the world’s population, occurs when dietary gluten triggers a damaging immune response. It often causes digestive symptoms such as bloating, abdominal pain and diarrhea. It can also cause anemia and excessive tiredness, and it is associated with osteoporosis, other autoimmune disease, and some types of cancer.

Definitive diagnosis currently requires invasive biopsy, so improved diagnostics and treatments are urgently needed. The only approved treatment is a gluten-free diet, and there is no known cure.

Enterprise Deputy Vice-Chancellor Ken Sloan said the research agreement with Janssen is another example of Monash actively engaging with industry. “Monash University remains committed to moving research forward for the betterment of human health, creating new avenues and opportunities that may lead to tangible benefits for the broader community,” Sloan said.

According to Monash Biomedicine Discovery Institute Director John Carroll, the collaboration is an excellent illustration of that strategy in practice. “This collaboration is another example of how Monash BDI’s strong clinical relationships and industry engagement aim to accelerate the development of diagnostic and preventative treatments,” Carroll said.

Source: Hospital and Healthcare

Posted under: University-Industry Engagement Week

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