Tech Transfer eNews Blog

UConn start-up advances novel manufacturing technology for pharmaceutical nanoparticles


By Jesse Schwartz
Published: November 18th, 2020

A start-up from the University of Connecticut (UConn) is advancing a continuous manufacturing technology for pharmaceutical nanoparticles.

DIANT Pharma’s technology is specifically designed for liposomal formulations but can be applied to a wide range of nanoparticles. It has several advantages over conventional manufacturing approaches, such as better efficiency, higher throughput and a smaller footprint, as the system is considerably smaller than a batch process and can occupy less space in a clean room, which also reduces costs.

DIANT’s technology arrives as many drug manufacturing operations are moving offshore due to high labor costs in the U.S. The new system, which continuously monitors for quality and can quickly identify a problem within the manufacturing process, could offer an affordable solution to U.S.-based companies, including those trying to produce a COVID-19 vaccine.

DIANT co-founders Antonio Costa and Diane Burgess, both researchers at UConn, have received more than $5 million in funding from the FDA to develop the technology, which they recently licensed from the university. DIANT also received support from various UConn commercialization programs and start-up incubators.

“When academic researchers and industry come together, we can find solutions to some of the world’s major challenges,” says Radenka Maric, vice president for research, innovation and entrepreneurship at UConn. “Diane is an internationally renowned scientist, and the success of this team is a prime example of how innovative research from preeminent researchers can transition from an idea in a lab to a technology that can help people around the world.”

Source: UConn Today

Posted under: Tech Transfer e-News

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