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Purdue researchers develop noninvasive devices to measure uric acid levels in sweat

Researchers at Purdue University have developed noninvasive medical devices to improve the monitoring and treatment of a range of physiological and psychological conditions.

The wearable devices use sensors known as EPICS to provide repeated monitoring of uric acid (UA) levels in human sweat over long periods of time.

“Variation in UA concentration could indicate physiological diseases such as gout, hyperuricemia and hypertension, as well as psychological conditions such as anxiety and depression,” says Wenzhou Wu, associate professor at Purdue and head of the research team behind the technology.

The EPICS have higher sensitivity and better wearability than current wearable sensors that measure UA levels in sweat. They also serve as a less invasive, more rapid method than testing UA levels in blood.

“The intrusive nature of collecting blood and the delay between sample collection and analysis are major hindrances, especially to personalized remote treatments like flare-up prevention and just-in-time nutrition control,” Wu says. “Monitoring UA levels in sweat samples has the advantages of being noninvasive and offering real-time results.”

Wu disclosed the technology to the Purdue Innovates Office of Technology Commercialization, which has applied for a patent. The office is currently seeking industry partners to develop and commercialize the technology.

Source: Purdue Research Foundation News

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